Host suppression of quorum sensing during catheter-associated urinary tract infections

Prevention of Catheter-Associated Urinary Tract Infections

Urinary catheter placement is an extremely common medical intervention. It can be used either temporarily, for example to drain a full bladder, to monitor urine output or it can be indwelling for long term drainage. While urinary catheters are a safe medical practice, complications can and do arise from their use and can be a source of morbidity for hospital or nursing home residents. The term ...

[Prevention of Catheter-Associated Urinary Tract Infections].

With a share of 22.4%, nosocomial urinary tract infections (nUTIs) are among the most frequent infections acquired in hospitals, along with surgical site infections (24.7%), pneumonia (21.5%), clostridium difficile infections (6.6%) and primary sepsis (6%) 1. 80% of all nUTIs are associated with indwelling urinary catheters, with 12-16% of all hospitalised patients and up to 81.8% of all intens...

Reducing catheter associated urinary tract infections.

Quorum sensing and virulence of Pseudomonas aeruginosa during urinary tract infections.

INTRODUCTION In the opportunistic pathogen Pseudomonas aeruginosa, the production of several virulence factors depends on quorum sensing (QS) involving N-acylhomoserine lactone signal molecules. In vitro studies have suggested that the QS system is crucial in the pathogenesis of P. aeruginosa. However, it is unclear whether QS systems of P. aeruginosa play the same role during infections. MET...

Guidelines for prevention of catheter-associated urinary tract infections.

The most common site of nosocomial infection, involving more than 400 000 patients in this country annually, is the catheterized urinary tract. These infections cause significant morbidity, prolong hospital stay, increase hospitalization costs, and contribute to mortality caused by Gram-negative septicemia. Strict adherence to appropriate infection control procedures is necessary if the inciden...